Indications

Person staring off into the distance
Person staring off into the distance

BREYANZI® MAKES COMPLETE AND
LASTING REMISSION POSSIBLE

RECLAIM TOMORROW: ACHIEVE PROLONGED RESULTS WITH A ONE-TIME INFUSION*

Explore the clinical trial results below or view the potential side effects.

COMPLETE REMISSION IS POSSIBLE AFTER 2 OR MORE PRIOR TREATMENTS

Who was in this study and what were the results?

A clinical study evaluated 113 adult patients with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that had come back or stopped responding to treatment after 2 other types of treatment, including a Bruton tyrosine kinase (BTK) inhibitor and a B-cell lymphoma 2 (BCL-2) inhibitor.

Nearly 1/2 of all people had their cancer shrink or disappear

This is called overall response, which was seen in 29 out of 65 people. It measures a decrease or disappearance of cancer in the body. Half of the patients with an overall response were still responding at 35.3 months.

1 in 5 people showed no signs of cancer
This is called complete response, which was seen in 13 out of 65 people. Complete response means there were no signs of cancer in the body, but it does not mean the cancer has been cured. For patients with a complete response, 87.5% of patients were still responding at 18 months. The rest of the people who responded (16 out of 65 people) experienced a decrease of cancer in the body. This is called partial response.
RAPID REMISSION WAS SEEN, WITH MANY PEOPLE EXPERIENCING COMPLETE REMISSION WITHIN 1 MONTH

In the clinical study, complete or partial response, was seen around 1 month (median) after infusion. This ranged from 0.8 months to 17.4 months.

*The treatment process includes blood collection, CAR T cell creation, administration, and side-effect monitoring. No maintenance therapy for the lymphoma is needed after Breyanzi as long as you are responding to treatment.

 

These are the results experienced by people in the Breyanzi clinical studies. Your results may be different.

Chronic/Small Lyphocytic Leukemia Patient Brochure cover.

Learn more about Breyanzi for the treatment of R/R CLL/SLL

Get to know this CAR T cell therapy in detail, including the clinical trial results, safety information, and treatment process. 

R/R, relapsed or refractory.



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2009-US-2400823, 2009-US-2400825 12/24