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WHAT IS CAR T THERAPY?

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BREYANZI® IS A CAR T CELL THERAPY: A DIFFERENT KIND OF CANCER TREATMENT

Breyanzi is not a stem cell transplant or chemotherapy. It is a chimeric antigen receptor (CAR) T cell therapy—a type of treatment that uses your own immune cells to fight your cancer.

The key to Breyanzi is your own white blood cells

Your white blood cells (T cells) are combined with a hook on the surface of the cell called a CAR receptor, which guides them to better locate and fight your cancer cells.

Illustration of a person holding a key

THE 3 B’S OF BREYANZI CAR T: BORROW, BOOST, BENEFIT

Illustration of a patient undergoing apheresis in a CAR T treatment center

BORROW

The first step is to borrow or extract your white blood cells (T cells) through blood collection. This process is called apheresis, in which blood is collected, part of the blood is taken out (in this case, white blood cells), and the rest is returned to you.

Illustration of a T cell combined with CAR receptor, creating CAR T cell

BOOST

Then your white blood cells (T cells) are given a boost with the addition of a receptor called a CAR. That’s how they become your Breyanzi CAR T cells.

Illustration of a patient recovering in a CAR T treatment center

BENEFIT

Finally, the CAR T cells are infused back into your body so that you may benefit from their enhanced cancer-targeting abilities. See below for how this treatment works within your body.

HOW DOES BREYANZI START WORKING IN THE BODY AFTER THE INFUSION?
Illustration of a CAR T cell attaching to a cancer cell

AFTER INFUSION

  • Once your Breyanzi CAR T cells are made, they'll be put back into your body through an infusion and will begin to multiply
  • The CARs will help guide your white blood cells (T cells) to better locate and fight your cancer cells
  • The CAR T cells attach to the marker on the cancer cells and some normal cells, allowing Breyanzi and your body to find and fight cancer
Quote: My doctor said to think of [my CAR T cells] as little soldiers that are there to help kill the cancer cells. The cells that were altered would recognize cancer cells, as well as some healthy cells, and attack them. Stated by Karla, a real Breyanzi patient.

Is it time for Breyanzi?

Breyanzi may be an option, even if other treatments have not worked or stopped working.

Want more detail about how the Breyanzi treatment process works?

Read an in-depth description of each step of the process.



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